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Advanced Molecular Diagnostics
Our multidisciplinary facility is dual ISO-accredited by the American Association of Laboratory Accreditation (A2LA), demonstrating our commitment to quality and excellence in the fields of Clinical Diagnostics and Biobanking.
Biobanking
Our goal is thus to ensure that functionally our bioarchive serves more than just a storage facility; it is a gateway to future insights and discoveries in the realm of precision medicine.
Molecular Pathology Excellence
Precision Medicine in Practice
Revna Biosciences is dedicated to the study and diagnosis of diseases through the examination of molecules within organs, tissues, or bodily fluids.
Our multidisciplinary lab is ideally suited to meet the requirements of molecular pathology, which intersects with anatomic pathology, clinical pathology, molecular biology, biochemistry, proteomics, and genetics.
Our lab employs a variety of molecular pathology techniques across different specialties to diagnose and assess risk for a multitude of diseases.
These techniques include:
quantitative polymerase chain reaction (qPCR), multiplex PCR, digital PCR (dPCR), DNA microarray, in situ RNA sequencing, DNA sequencing, molecular profiling of pathogens, and analysis of bacterial genes for antimicrobial resistance.
Pioneering Oncology Solutions with a Focus on Liquid Biopsy
RevnaBio offers a comprehensive suite of oncology assays, including PCR (qPCR and dPCR) and NGS (for solid and hematologic cancers).
These assays provide actionable insights into key driver mutations (ESCAT Tier-1 markers) for a wide range of cancers. Our focus areas include breast, colorectal, lung, thyroid, glioma, hepatocellular carcinoma, cervical, acute myeloid leukaemia, acute promyelocytic leukaemia, chronic myeloid leukaemia, cholangiocarcinoma, and cutaneous melanoma.
A significant highlight of our service is the use of liquid biopsy option in the majority of our oncology assays. Liquid biopsy, which involves a simple blood draw, allows us to detect and analyse tumour DNA or RNA fragments circulating in the blood. This approach offers a more comfortable and less invasive experience for patients, and can provide real-time insights into tumour evolution, response to therapy, and potential resistance mechanisms.
Microbiology Expertise
Harnessing the Power of Precision Medicine
Revna Biosciences, leveraging its ISO accreditation in the sub-specialties of virology and bacteriology, is equipped to address a wide range of unmet needs in the general microbiology space. Our labs are capable of handling level 3 infectious viral and bacterial pathogens, thanks to rigorous protocols and cutting-edge instrumentation.
By integrating the principles of molecular pathology, we delve deeper into the molecular mechanisms of disease, leading to more accurate diagnoses and targeted treatments. Our focus on emerging pathogens ensures we are prepared to support the tackling of new and re-emerging diseases, playing a vital role in safeguarding public health.
Genomics and Molecular Assays
We conduct a wide array of genomics and molecular assays with precision and reliability from foundational processes such as extraction, RNA and DNA purification, quantification, and storage.
Revna Biosciences offers specialized assays for a
variety of conditions and diseases. These include:
Solid Tumours
- ALK/ROS1/RET/MET
- BRAF
- Dihydropyrimidine Dehydrogenase (DPYD)
- Epidermal Growth Factor Receptor (EGFR)
- Epidermal Growth Factor Receptor Plus (EGFR Plus)
- Estrogen Receptor 1 (ESR1)
- IDH1-2
- Kirsten Rat Sarcoma (KRAS)
- Microsatellite Instability
- Neurotrophic Tyrosine Receptor Kinase (NTRK) Fusion
- PIK3CA
- UGT1A1
- Neuroblastoma Rat Sarcoma
- O-6-Methylguanine-DNA Methyltransferase
- Thyroid (KRAS, NRAS, HRAS, BRAF)
- Thyroid Fusion (RET/PTC1, RET/PTC2, RET/PTC3, PAX8/PPARG)
Haematological Cancers
- AML1-ETO Fusion
- BCR-ABL Fusion
- BCR-ABL p190
- BCR-ABL p210
- CBFB-MYH11 Fusion
- PML-RARA
- NPM1 Screening
- NPM1 Quantitative
- FMS-like tyrosine kinase 3
Tumour Markers
- Cytokeratin 19 Fragment
- Prostate Specific Antigen
- Free Prostate-Specific Antigen
- Total Prostate-Specific Antigen
- Gastrin 17
- Human Epididymis Protein 4
- Neuron-Specific Enolase
- Cancer Antigen-125
- Cancer Antigen 15-3
- Cancer Antigen 19-9
- Cancer Antigen 242
- Cancer Antigen 50
- Cancer Antigen 724
- Carcinoembryonic Antigen
- Squamous Cell Carcinoma Antigen
- Progastrin-Releasing Peptide
- Progesterone Receptor
- Pepsinogen I
- Pepsinogen II
- Alpha Feto Protein
Cytopathology/Histopathology
- Conventional Pap Smear
- Pap Smear for Cytology
- Histology
- Fluid cytology
- Immunohistochemistry
Infectious Disease (Panel Test)
- Respiratory Pathogen Detection Panel
- Sexually Transmitted Infections (STIs) Pathogen Detection Panel
- Blood Pathogen/Sepsis Panel
- Meningitis/Encephalitis Pathogen Detection Panel
Infectious Disease (Single Tests)
- BKV (Quantitative)
- CMV (Quantitative)
- CT/NG (Qualitative)
- EBV (Quantitative & Qualitative)
- Hepatitis B Viral Load
- Hepatitis C Viral Load
- HSV 1/2 (Quantitative & Qualitative)
- Human Immunodeficiency Virus Type - 1 (Qualitative)
- Human Immunodeficiency Virus Type - 1 (Quantitative)
- Human Papilloma Virus Screening & Genotyping (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68)
- QuantiFERON Latent TB
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) (Qualitative)
Biochemistry
- Albumin Creatinine Ratio
- Calcium
- Serum Electrolytes (Na, K, Cl)
- Kidney Function Test
- Lactate Dehydrogenase
- Lipid Profile
- Liver Function Test
- Phosphate
- Random Blood Sugar
- Serum Protein Electrophoresis
- Uric Acid
- Urinary Total Protein
- Urine Sodium
- Urine Calcium
- Fasting Blood Sugar
- Thyroid Function Test
- Serum Amylase
Haematology
- Blood Film for Malaria Parasites
- Clotting Profile
- Erythrocyte Sedimentation Rate
- Full Blood Count
- Haemoglobin Electrophoresis
- Sickling Test
- Blood Film Comment
Immunology
- Blood Film for Malaria Parasites
- Clotting Profile
- Erythrocyte Sedimentation Rate
- Full Blood Count
- Haemoglobin Electrophoresis
- Sickling Test
- Blood Film Comment
Microbiology
- Urine Culture and Susceptibility
- Urine Routine Examination
- High Vaginal Swab Culture & Susceptibility
- High Vaginal Swab Routine Examination
Serology
- Widal-IgM & IgG
- Treponema Pallidum
- Venereal Disease Research Laboratory (VDRL)
- Human Immunodeficiency Antigen & Antibody
- Hepatitis C Virus Antibodies
- Hepatitis B Envelope Antibody
- Hepatitis B Envelope Antigen
- Hepatitis B Profile
- Hepatitis B Surface Antigen (ELISA)
- Hepatitis B Surface Antigen (Rapid)
- Hepatitis B Total Core Antibody
- HIV-1 & 2 Antibody
- Malaria Pf (Rapid)
Cardiovascular
- Heart-Type Fatty Acid-Binding Protein
- High-Sensitivity Cardiac Troponin I
- High-Sensitivity Cardiac Troponin T
- Myoglobin
- Creatine Kinase MB
- Cardiac Enzymes
- Cardiac Profile
- N-terminal Pro b-type Natriuretic Peptide
- Brain Natriuretic Peptide
- Troponin I
- Troponin T
- D-Dimer
Hormones
- Anti-Müllerian hormone
- Beta-Human Chorionic Gonadotropin
- Estradiol
- Follicle-Stimulating Hormone
- Human Growth Hormone
- Luteinizing Hormone
- Progesterone
- Prolactin
- Sex Hormone-Binding Globulin
- Testosterone
- Unconjugated Estriol
Thyroid
- Thyroglobulin
- Thyroglobulin Antibodies
- Thyroid Peroxidase Antibody
- Thyroid Stimulating Hormone
- Total T3
- Total T4
- Free T3
- Free T4
Bone Metabolism
- 25-hydroxyvitamin D3
- Osteocalcin
- Parathyroid Hormone
Hypertension
- Aldosterone
- Cortisol
- Renin
Inflammation
- High-Sensitivity C-reactive Protein & C-Reactive Protein
- Interleukin-6
- Procalcitonin
- Serum (rep top/plain) tube Amyloid A
- C Reactive Protein
Glycometabolism
- Insulin
- Insulin Auto-Antibody
- C-Peptide
- Glycosylated Hemoglobin (HbA1c)
Anaemia
- Vitamin B12
- Ferritin
- Iron Studies
- Total Iron Binding Capacity
Hepatic Fibrosis
- Type III Procollagen Peptide
- Hyaluronic acid
- Laminin
- Cholyglycine
- Collagen type IV
Renal Function
- Neutrophil Gelatinase-associated Lipocalin
- Urine Microalbumin
Therapeutic Drug Monitoring
- Tacrolimus
- Digoxin
- Cyclosporin A
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